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3 Companies with Results for pbpk modeling 1 - 3 of 3

Simulations Plus

42505 10th Street West Lancaster, CA 93534 Tel: +1 661 723-7723

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Resource Center - Simulations Plus

... in Pediatric Populations Using GastroPlus Recent Webinars GastroPlus™ PBPK modeling as a tool to ensure target performance of ... and New Questions Webinars Incorporating transporter kinetics into PBPK models Journal Articles Integrating in vitro, modeling, and in ...

Resource Center - Simulations Plus

... Kohonen Self-Organizing Maps Posters Physiologically based pharmacokinetic (PBPK) model for intramuscular injection of aripiprazole Posters QSAR-based ...

Resource Center - Simulations Plus

... of food effects for Compound A tablet using PBPK model Journal Articles Characterising Drug Release from Immediate-Release ... orbito IMI project Journal Articles Physiologically Based Pharmacokinetic (PBPK) Modeling of Pharmaceutical Nanoparticles Journal Articles Exploring and validating ...

PBPK Modeling | DDI Predictions | Formulation Development | Physiology Models

GastroPlus™ leads the PBPK modeling revolution. See how we combine a user-friendly interface and powerful science to provide solutions across industries.

Pharmacokinetics of Biologics | PBPK Modeling of Large Molecules

Use the Biologics Module to easily create PBPK models and simulate the pharmacokinetics of biologics - for both mAbs and ADCs. ... GastroPlus™ PBPK modeling software – from discovery through development… Watch: GastroPlus™ 9.5 Promo Video Software | GastroPlus™ | Biologics Choose a Module: ...

Drug Administration Routes | Dermal Delivery | Inhaled Products | Injection

... Additional Dosage Routes Module in GastroPlus extends your PBPK models by simulating various drug administration routes. ... GastroPlus™ PBPK modeling software – from discovery through development… Watch: GastroPlus™ 9.5 Promo Video Software | GastroPlus™ | Additional Dosage Routes Choose ...

PBPK Software | Physiologically Based Pharmacokinetic Modeling

GastroPlus™ PBPK modeling software – from discovery through development… Watch: GastroPlus™ 9.5 Promo Video Software | GastroPlus™ | PBPKPlus™ Choose a Module: ...

PBPK Modeling | Pharmacometrics | Clinical Pharmacology | PK/PD Modeling | Clinical Trial Data Analysis

... lots of analysis… Learn how our experts and PBPK modeling technology provides you with solutions at every phase ... we are able to bridge physiologically-based pharmacokinetic (PBPK) modeling with population PK/PD and clinical trial data ...

PBPK Consulting Services | PBPK Modeling Analysis/Simulation

PBPK Modeling and Analysis/Simulation Services | Pharmaceutical | PBPK Modeling and Analysis/Simulation Better understand the PBPK behind your compounds. Simulations Plus offers PBPK consulting services using our GastroPlus™ software – the pharmaceutical industry’ ...

PBPK Modeling Workshops | Population PK Data Analysis Courses

... advancements in model-driven development by attending our PBPK modeling workshops or population PK data analysis courses - register ... science… today. Encouragement from regulatory agencies to incorporate PBPK modeling and population PK/PD data analysis to help ...

Simulations Plus | Modeling & Simulation Software | Consulting Solutions

... of ADME-Tox property predictions, physiologically-based pharmacokinetic (PBPK) modeling software, and pharmacometric consulting solutions. ... new version has something for everyone, including improved PBPK models for biologics, IM and SC injection routes, updated ...

PBPK Modeling Workshop | Population PK Analysis | NONMEM Workshop

... science - today! Register for one of our leading PBPK modeling workshops or population PK data analysis courses. ... PBPK Modeling & Population PK Data Analysis Workshops Watch: Workshops 2017 Promo Video PBPK Modeling & Population PK Data Analysis ...

Nonlinear Pharmacokinetics | PBPK Models | Drug Metabolism | Transport

... allows you to incorporate nonlinear pharmacokinetics into your PBPK models. Learn how your peers are using it. ... GastroPlus™ PBPK modeling software – from discovery through development… Watch: GastroPlus™ 9.5 Promo Video Software | GastroPlus™ | Metabolism & Transporter Choose a ...

Resource Center - Simulations Plus

... LARGE data sets Webinars Incorporating transporter kinetics into PBPK models Recent Webinars GastroPlus™ PBPK modeling as a tool to ensure target performance of ...

Partners and Collaborators - Simulations Plus

... and Pharmacodynamics CRO Partners The demand for QSAR/PBPK modeling support continues to grow, and we encourage CROs ... of the momentum behind the increased use of PBPK modeling has been driven by regulatory agencies around the ...

Resource Center - Simulations Plus

... drug-drug interaction potential using physiologically based pharmacokinetic (PBPK) modeling approach: A case study of caffeine and ciprofloxacin ... science of curating QSAR data Posters Novel Skin PBPK model in Action: Clindamycin and Tazarotene Modeling Journal Articles ...

Pharmacodynamics and Pharmacokinetics | PK/PD Models

Extend your PBPK models in GastroPlus by finding relationships between pharmacodynamics and pharmacokinetics with the PDPlus Module. ... GastroPlus™ PBPK modeling software – from discovery through development… Watch: GastroPlus™ 9.5 Promo Video Software | GastroPlus™ | PDPlus™ Choose a Module: ...

PBPK Simulations | ADMET Predictions | QSAR-PBPK Marriage

GastroPlus™ PBPK modeling software – from discovery through development… Watch: GastroPlus™ 9.5 Promo Video Software | GastroPlus™ | ADMET Predictor™ Choose a ...

Overview - Simulations Plus

... modeling to assist with drug design efforts, bridge PBPK modeling with pharmacometrics/population PK/PD analyses, provide expanded ... way through regulatory filings, Simulations Plus can help. PBPK Modeling and Analysis/Simulation Better understand the PBPK behind ...

Drug Interactions | DDI Predictions | DDI Risk Assessment

GastroPlus™ PBPK modeling software – from discovery through development… Watch: GastroPlus™ 9.5 Promo Video Software | GastroPlus™ | Drug Drug Interaction Choose ...

IVIVC | Mechanistic IVIVC | In Vitro-In Vivo Correlation

GastroPlus™ PBPK modeling software – from discovery through development… Watch: GastroPlus™ 9.5 Promo Video Software | GastroPlus™ | IVIVCPlus™ Choose a Module: ...

Generic Drugs | Bioequivalence Study | IVIVC FDA | Formulation Development | Dissolution Method

... clock is ticking… Learn how our mechanistic PK/PBPK modeling solutions can help you file generic & 505(b)( ... possible? A small investment in the mechanistic PK/PBPK modeling solutions from Simulations Plus should pay huge dividends – ...

Company Overview - Simulations Plus

... Predictor ™. The combination of the industry’s leading PBPK modeling & simulation platform, with the #1-ranked QSAR models, ... feed into GastroPlus, which sets the standard for PBPK/PD modeling for oral (immediate and controlled release formulations), intravenous, ...

Software Products - Simulations Plus

... variety of aerospace and other problems. GastroPlus™ Our PBPK modeling & simulation software package which simulates intravenous, oral, oral cavity, ocular, inhalation, dermal/subcutaneous, and intramuscular absorption, PBPK/PD modeling, and drug-drug interactions (DDIs) in virtual human ...

Physiology Models | Deconvolution | Parameter Fitting | Model Building

GastroPlus™ PBPK modeling software – from discovery through development… Watch: GastroPlus™ 9.5 Promo Video Software | GastroPlus™ | Optimization Choose a Module: ...

Resource Center - Simulations Plus

... Candidate Optimization and Selection White Papers Application of PBPK Modeling in Generic Drug Evaluation

Pharmacokinetic Studies | PK Modeling | Compartmental PK Models

GastroPlus™ PBPK modeling software – from discovery through development… Watch: GastroPlus™ 9.5 Promo Video Software | GastroPlus™ | PKPlus™ Choose a Module: ...

Resource Center - Simulations Plus

... Studies Webinars Application of Cellular Permeability Simulation and PBPK Models to Capture

PBPK Modeling | ADME | Drug Safety | PK/PD Modeling | Allometry

Get to the clinic faster and with more confidence. Learn how our model-driven solutions at Simulations Plus can improve the efficiency of your preclinical ...

Resource Center - Simulations Plus

... Video Videos Application of Cellular Permeability Simulation and PBPK Models to Capture Significance of Transporter Effects on Dose ...

The Simulations Plus Customer Portal - Simulations Plus

... ways you can take advantage of our QSAR, PBPK, and/or pharmacometrics modeling & simulation solutions. You may login here to access ...

Toxicity modeling | Dermal administration | Oral cavity | Animal testing | Allergic response | Toxicokinetic modeling | Cosmetics | Food Additives

... safety. Similar agencies exist in other countries. ADMET modeling and PBPK simulations can be used to predict efficacy, safety, ...

Physicochemical property prediction | pKa | logP | logD | aqueous solubility

... Predictor module of GastroPlus ™ in order to perform PBPK simulations using predicted properties. Physicochemical property prediction The image below lists the models in ADMET Predictor’s PCB Module. Brief descriptions ...

toxicity and exposure modeling | toxicokinetics | PBTK

... relevant properties in order to perform a full PBPK simulation. For example, one can simulate an oral rat acute toxicity test. GastroPlus will predict the fraction absorbed (Fa) using it Advanced Compartmental Absorption and Transit Model (ACAT™). Low Fa values result in reduced chemical ...

Software Installation - Simulations Plus

... incorporate a much larger set of differential equations, PBPK simulations ... a cloud based model using Amazon Web Services (EC2), a scalable, reliable, ...

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... Predictor™ . The combination of the industry’s leading PBPK modeling & simulation platform, with the #1-ranked QSAR models, ... feed into GastroPlus, which sets the standard for PBPK/PD modeling for oral (immediate and controlled release formulations), intravenous, ...

Dissolution Technologies

9 Yorkridge Trail Hockessin, DE 19707 Tel: 302-235-0621

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Dissolution Technologies - Industry News - Simulations Plus Releases GastroPlus™ Version 9.5

... has released version 9.5 of its flagship PBPK modeling program, GastroPlus™. Dr. Viera Lukacova, team leader and ... the recently released draft guidance documents focused on PBPK modeling from the U.S. FDA and the European ...

Dissolution Technologies

... has released version 9.5 of its flagship PBPK modeling program, GastroPlus™. Simulations Plus Finalizes Distributor Agreement with ...

Dissolution Technologies - Industry News

... How to handle supersaturation? Some participants asserted that PBPK modeling is not ready for prime time (e.g., ...

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... has released version 9.5 of its flagship PBPK modeling program, GastroPlus™. Dr. Viera Lukacova, team leader and ... the recently released draft guidance documents focused on PBPK modeling from the U.S. FDA and the European ...

Cyprotex

269-353-5555

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