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69 Companies with Results for metabolism 1 - 10 of 69

BioreclamationIVT

PO Box 770 Hicksville, NY 11802-0770 Tel: 516-483-1196

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BioreclamationIVT is a worldwide provider of biological and in vitro products to pharmaceutical and biotechnology ...

Simulations Plus

42505 10th Street West Lancaster, CA 93534 Tel: +1 661 723-7723

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Resource Center - Simulations Plus

... risk assessment Journal Articles Predicting the extent of metabolism using in vitro permeability rate measurements and in ... and cytotoxicity Journal Articles The prediction of drug metabolism, tissue distribution, and bioavailability of 50 structurally diverse ...

CYP metabolite prediction | CYP kinetic parameters | CYP inhibition | UGT

ADMET Predictor's Metabolism Module contains a collection of QSAR models for CYP metabolite prediction. It also contains CYP inhibition models and more!

Nonlinear Pharmacokinetics | PBPK Models | Drug Metabolism | Transport

The Metabolism and Transporter Module allows you to incorporate nonlinear pharmacokinetics into your PBPK models. Learn how your peers ... Watch: GastroPlus™ 9.5 Promo Video Software | GastroPlus™ | Metabolism & Transporter Choose a Module: Metabolism & Transporter What is ...

Resource Center - Simulations Plus

... on Oral Drug Absorption: Sensitivity Analyses Journal Articles Metabolism of Carfentanil, an Ultra-Potent Opioid, in Human ... state vs. healthy conditions Journal Articles Absorption, distribution, metabolism, excretion, and kinetics of 2,3,3,3- ...

Resource Center - Simulations Plus

... New Questions Posters Modeling of Active Transport and Metabolism for in vitro Suspended and Sandwich Hepatocyte Assays ... Predictions in Pediatric Populations Using GastroPlus Journal Articles Metabolism of Carfentanil, an Ultra-Potent Opioid, in Human ...

Resource Center - Simulations Plus

... and physiologically based modeling of cytochrome P450 mediated metabolism in beagle dog gut wall and liver Journal ... systemic availability Posters Modeling of Active Transport and Metabolism for in vitro Suspended and Sandwich Hepatocyte Assays ...

PBPK Simulations | ADMET Predictions | QSAR-PBPK Marriage

... ADMET Predictor module of GastroPlus predicts the physicochemical, metabolism, and pharmacokinetic parameters needed to run full PBPK ... from structure of all physicochemical, pharmacokinetic, and CYP metabolism kinetic parameters required for the GastroPlus PBPK simulations. ...

ADMET property prediction | QSPR | physicochemical | CYP metabolism

... humans and the environment. The ADMET (absorption, distribution, metabolism, excretion, and toxicity) properties of your molecules are ... properties including solubility, logP, pKa, sites of CYP metabolism, and Ames mutagenicity. The ADMET Modeler™ module in ...

PBPK Software | Physiologically Based Pharmacokinetic Modeling

... can employ fixed intrinsic clearance and with the Metabolism and Transporter Module , saturable (Michaelis-Menten) metabolism and transport (influx and efflux) can be incorporated. ...

Resource Center - Simulations Plus

... Library with In Silico QSAR Models for Xenobiotic Metabolism and Toxicity Webinars What’s New in GastroPlus™ ... Webinars Physicochemical and biopharmaceutical properties Webinars In Silico Metabolism Webinar Webinars Matched Molecular Pairs Webinar Webinars Toxicity ...

Terms of Use - Simulations Plus

... hereunder known as: GastroPlus™, GastroPlus™ Optimization Module, GastroPlus™ Metabolism and Transporter Module, GastroPlus™ IVIVCPlus™ Module, GastroPlus™ PKPlus™ ...

Resource Center - Simulations Plus

... Center Login Posters Modeling of Active Transport and Metabolism for in vitro Suspended and Sandwich Hepatocyte Assays ...

Caco-2 Cells | In Vitro Permeability | Hepatocytes | Drug Transporters

... the MembranePlus permeability models. You enter limited physicochemical & metabolism/transporter data (if applicable), set up your permeability ...

In Vitro Hepatocyte Modeling | Cellular Simulations

... Predictor module of MembranePlus predicts the physicochemical & CYP metabolism inputs for your in vitro hepatocyte & permeability simulations.

Design Module

... activity, but also to ensure that physicochemical, biopharmaceutical, metabolism, and toxicity properties are also acceptable.

Corporate Profile - Simulations Plus

... Inc. is the leading developer of Absorption, Distribution, Metabolism, Excretion and Toxicity (ADMET) modeling and simulation software ...

Toxicity prediction | QSTR | Ames mutagenicity | hERG inhibition

... 5 individual strains of Salmonella with or without metabolic activation. The Ames Mutagenicity is a measurement of ... body. Lysosomes are cellular organelles containing enzymes which metabolize waste materials to facilitate their excretion. In individuals ...

toxicity and exposure modeling | toxicokinetics | PBTK

... body and into various tissues and organs. High metabolic clearance of the chemical can reduce its toxicity. ... in reduced chemical exposure. The compound can be metabolized in the gut wall and the liver by ...

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... risk assessment Journal Articles Predicting the extent of metabolism using in vitro permeability rate measurements and in ... and cytotoxicity Journal Articles The prediction of drug metabolism, tissue distribution, and bioavailability of 50 structurally diverse ...

R&D Services Pharma Consulting

10519 Reeder St. Overland Park, KS 66214 Tel: 913-481-4309

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Dr. Thomas N. Thompson — R&D Services

... available to them in the areas of drug metabolism, ADME and pharmacokinetics. ... the fields of preclinical and clinical pharmacokinetics, drug metabolism, and ADME, and has worked in the Pharma, ...

PUBLICATIONS — R&D Services

... available to them in the areas of drug metabolism, ADME and pharmacokinetics. ... Verlag, 2010, chapter 13, pp 285-313 Drug Metabolism In-vitro and In-vivo Results: How do ...

ABOUT US — R&D Services

... available to them in the areas of drug metabolism, ADME and pharmacokinetics. ... available to them in the areas of drug metabolism, ADME and pharmacokinetics. In the Drug Discovery phase, ...

OUR SERVICES — R&D Services

... available to them in the areas of drug metabolism, ADME and pharmacokinetics. ... most aspects of preclinical and clinical pharmacokinetics, drug metabolism and ADME studies from both logistic and strategic ...

R&D Services

... available to them in the areas of drug metabolism, ADME and pharmacokinetics. ... in a wide array of disciplines, including drug metabolism/pharmacokinetics, toxicokinetics, and bioanalysis. At RDS, we provide ...

Dr. Gregory M. Kochak — R&D Services

... available to them in the areas of drug metabolism, ADME and pharmacokinetics. ... available to them in the areas of drug metabolism, ADME and pharmacokinetics.

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... in a wide array of disciplines, including drug metabolism/pharmacokinetics, toxicokinetics, and bioanalysis. At RDS, we provide ...

Myriad RBM

3300 Duval Road Austin, TX 78759 Tel: 512-835-8026

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Bibliography - Myriad RBM

... Neurological Disease MicroRNA-33-dependent regulation of macrophage metabolism directs immune cell polarization in atherosclerosis (2015) Ouimet ... J, Morgan S, Critchlow SE, Barry ST Cell Metabolism Therapy Indications Cancer Diabetes and Metabolic Markers Mechanism- ...

Diabetes and Metabolic Markers - Myriad RBM

... Metabolic Markers MicroRNA-33-dependent regulation of macrophage metabolism directs immune cell polarization in atherosclerosis (2015) Ouimet ... J, Morgan S, Critchlow SE, Barry ST Cell Metabolism Therapy Indications Cancer Diabetes and Metabolic Markers Back ...

Cardiovascular - Myriad RBM

... Indications Cardiovascular MicroRNA-33-dependent regulation of macrophage metabolism directs immune cell polarization in atherosclerosis (2015) Ouimet ...

CardiovascularMAP® v. 3.0 - Myriad RBM

... J, Morgan S, Critchlow SE, Barry ST Cell Metabolism Therapy Indications Cancer Diabetes and Metabolic Markers Common ... Hoffmann U, Fox CS. Journal of Clinical Endocrinology & Metabolism 2014 Sep 16:jc20134296. [Epub ahead of print] ...

NeuroMAP™ v. 1.0 - Myriad RBM

... Yasaka M, Okada Y, Kiyohara Y, Kitazono T Metabolism Therapy Indications Neurological Disease The Impact of APOE ... proteomic analysis identifies sex-specific differences in lipid metabolism and inflammation profiles in adults diagnosed with Asperger ...

InflammationMAP® v. 1.0 - Myriad RBM

... Cytokines/Chemokine MicroRNA-33-dependent regulation of macrophage metabolism directs immune cell polarization in atherosclerosis (2015) Ouimet ... Therapy Indications Inflammation and Immune Response Diabetes and Metabolic Markers Cardiovascular Cytokines/Chemokine Markers of inflammation are ...

Translating Preclinical Pharmacology in Clinical Activity - Myriad RBM

... where he built and directed the pharmacology, drug metabolism, pathology and toxicology groups that supported ICOS Research ...

KidneyMAP® v. 1.0 - Myriad RBM

... Colhoun HM Kidney International Therapy Indications Diabetes and Metabolic Markers Kidney Function and Toxicity Comparison of Plasma ... Epub ahead of print] Therapy Indications Diabetes and Metabolic Markers Kidney Function and Toxicity CD47 Blockade Reduces ...

Metabolic Application Notes - Myriad RBM

... Get Started Contact FAQ's Blog Myriad RBM Metabolic Application Notes Abstract Myriad RBM’s quantitative, multiplexed, ... in nearly 30 publications on diabetes and other metabolic disorders as part of a targeted proteomics approach ...

More Information - Myriad RBM

... Application Notes Inflammation Application Notes Application Notes, Inflammation Metabolic Application Notes Application Notes, Metabolic Neuroscience Application Notes ...

Neuroscience Application Notes - Myriad RBM

... Notes, Cardiovascular Toxicology Application Notes Application Notes, Toxicology Metabolic Application Notes Application Notes, Metabolic

Cardiovascular Application Notes - Myriad RBM

... Notes, Toxicology Neuroscience Application Notes Application Notes, Neuroscience Metabolic Application Notes Application Notes, Metabolic

DiscoveryMAP® v. 3.3 - Myriad RBM

... 15 years of assay development for cytokines, chemokines, metabolic markers, hormones, growth factors, tissue remodeling proteins, angiogenesis ...

ExplorerMAP™ v. 1.0 - Myriad RBM

... therapy areas including inflammation, immune response, cardiovascular, neurological, metabolic and cancer. Quick Links Click or mouse over ...

Endocrine - Myriad RBM

... of Lipid Research Therapy Indications Cardiovascular Diabetes and Metabolic Markers Endocrine Back To Top 2010 Luteinizing hormone, ...

Gastrointestinal - Myriad RBM

... ahead of print] Therapy Indications Gastrointestinal Diabetes and Metabolic Markers Cox-2 expression, PGE2 and cytokines production ...

Miscellaneous - Myriad RBM

... Indications Miscellaneous Inflammation and Immune Response Diabetes and Metabolic Markers Behavioural Traits Propagate across Generations Via Segregated ...

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... Neurological Disease MicroRNA-33-dependent regulation of macrophage metabolism directs immune cell polarization in atherosclerosis (2015) Ouimet ... J, Morgan S, Critchlow SE, Barry ST Cell Metabolism Therapy Indications Cancer Diabetes and Metabolic Markers Mechanism- ...

DMSO Health & Safety | Gaylord Chemical

... is also found in natural waters and soil. Metabolism of DMSO in soil by microorganisms results in ... studies (Shirley et al.,1988) . Human and Animal Metabolism DMSO is metabolized in humans by oxidation to ...

Procipient®(Dimethyl Sulfoxide USP, Ph. Eur.) Grade Product Sheet - Gaylord Chemical

... are excreted in the urine. Its absorption, distribution, metabolism, and elimination (ADME) properties have been studied extensively ...

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Gaylord Chemical Company is the leading producer of Dimethyl Sulfoxide (DMSO), with a product range ...

Powers Scientific, Inc.

PO Box 268 Pipersville, PA 18947 Tel: 800-998-0500

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Blog | Powers Scientific

... The process is referred to as crassulacean acid metabolism, or CAM, which is named for the family ...

Minimizing Water Loss in Plants w/ Genes | Powers Scientific

... The process is referred to as crassulacean acid metabolism, or CAM, which is named for the family ...

Trying to Turn Back the Aging Clock | Powers Scientific

... therapy would activate senescent cells (cells that are metabolically active but do not divide), which could increase ...

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... The process is referred to as crassulacean acid metabolism, or CAM, which is named for the family ...

Avanti Polar Lipids, Inc.

700 Industrial Park Drive Alabaster, AL 35007 Tel: 205-663-2494

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Products | Avanti Polar Lipids

... Glycosphingolipids Phosphosphingolipids Phytosphingosine & Derivatives Receptor Agonist/Antagonist Sphingolipid Metabolism Sphingomyelin Sphingosines Stable Isotopes & ESR Probes 13C Probes ...

Avanti Awards in Lipids | Avanti Polar Lipids

... in the understanding of Biophysics of lipids, including metabolism, enzymology, structure and membranes. 2017 – Jean-Marie Ruysschaert ...

Bioactive Lipids | Avanti Polar Lipids

... Substrates LPA & Cyclic LPA Inhibitors Inhibitors of Sphingolipid Metabolism Inhibitors of Phospholipase D Inhibitors Of Carnitine Palmitoyltransferase ...

Sphingolipids | Avanti Polar Lipids

... Sphingolipids Products Buy Lipids Sphingolipids Bioactive Ceramides Sphingolipid Metabolism Inhibitors Internal Standards Receptor Agonist/Antagonist S1P Antagonist ...

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... Glycosphingolipids Phosphosphingolipids Phytosphingosine & Derivatives Receptor Agonist/Antagonist Sphingolipid Metabolism Sphingomyelin Sphingosines Stable Isotopes & ESR Probes 13C Probes ...

Alturas Analytics

1324 Alturas Drive Moscow, ID 83843 Tel: (208) 883-3400

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Poster Presentations | Alturas Analytics

... AAPS October 14-18th 2012, Chicago, IL. Dextromethorphan Metabolism Profiling by the Analysis of Dried Matrix Samples ...

Our Blog - News - Events | Alturas Analytics

... the largest scientific societies dedicated to investigating the metabolism and disposition of chemicals in biological systems. Alturas ...

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... AAPS October 14-18th 2012, Chicago, IL. Dextromethorphan Metabolism Profiling by the Analysis of Dried Matrix Samples ...

PPD® Laboratories

929 North Front Street Wilmington, NC 28401-3331 Tel: 919-380-2000

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Endocrine and Metabolic Therapeutic Expertise | PPD

... TRIAL Menu Share this Contact Us Endocrine and Metabolic Therapeutic Expertise The need for more effective treatments for metabolic and endocrine disorders has never been greater, yet ...

Therapeutic Expertise | PPD

... large, global, multicenter Phase III trials. Endocrine and Metabolics Expedited recruitment, international regulatory expertise and operational teams ...

Healthy Clinical Trial Volunteers for Phase I Trials - PPD

... healthy volunteers, specifically how the compound is absorbed, metabolized and excreted. This is not testing to determine ...

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... TRIAL Menu Share this Contact Us Endocrine and Metabolic Therapeutic Expertise The need for more effective treatments for metabolic and endocrine disorders has never been greater, yet ...

Caprion Biosciences Inc

201 President-Kennedy Ave, Suite 3900 Montreal, QC H2X 3Y7 Tel: 514-360-3600

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Management : Caprion

... for indications such as cancer, as well as metabolic and infectious diseases. Prior to joining Caprion, Patrick ... diverse disease areas such as oncology, inflammation, and metabolic disease, and has broad experience in target protein ...

Hub of Science : Caprion

... of other innovative proprietary protein diagnostic tests for metabolic and infectious diseases that are being developed by ... its own in-vitro diagnostic products targeting cancer, metabolic and infectious diseases. With research sites in Montreal, ...

Hub of Science : Caprion

... collaboration with Boehringer Ingelheim to identify biomarkers of metabolic and inflammatory disease using Caprion's CellCarta proteomics ...

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... for indications such as cancer, as well as metabolic and infectious diseases. Prior to joining Caprion, Patrick ... diverse disease areas such as oncology, inflammation, and metabolic disease, and has broad experience in target protein ...

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